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DamageDetective  

Detecting Damaged Cells in Single-Cell RNA Sequencing Data
View on CRAN: Click here


Download and install DamageDetective package within the R console
Install from CRAN:
install.packages("DamageDetective")

Install from Github:
library("remotes")
install_github("cran/DamageDetective")

Install by package version:
library("remotes")
install_version("DamageDetective", "1.0.0")



Attach the package and use:
library("DamageDetective")
Maintained by
Alicen Henning
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2025-04-03
Latest Update: 2025-04-03
Description:
Detects and filters damaged cells in single-cell RNA sequencing (scRNA-seq) data using a novel approach inspired by 'DoubletFinder'. Damage is detected by measuring the extent to which cells deviate from artificially damaged profiles of themselves, simulated through the probabilistic escape of cytoplasmic RNA. As output, a damage score ranging from 0 to 1 is given for each cell providing an intuitive scale for filtering that is standardised across cell types, samples, and experiments.
How to cite:
Alicen Henning (2025). DamageDetective: Detecting Damaged Cells in Single-Cell RNA Sequencing Data. R package version 1.0.0, https://cran.r-project.org/web/packages/DamageDetective. Accessed 07 Aug. 2026.
Previous versions and publish date:
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Complete documentation for DamageDetective
Functions, R codes and Examples using the DamageDetective R package
Full DamageDetective package functions and examples
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