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DRviaSPCN  

Drug Repurposing in Cancer via a Subpathway Crosstalk Network
View on CRAN: Click here


Download and install DRviaSPCN package within the R console
Install from CRAN:
install.packages("DRviaSPCN")

Install from Github:
library("remotes")
install_github("cran/DRviaSPCN")

Install by package version:
library("remotes")
install_version("DRviaSPCN", "0.1.5")



Attach the package and use:
library("DRviaSPCN")
Maintained by
Junwei Han
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2021-12-09
Latest Update: 2025-01-09
Description:
A systematic biology tool was developed to repurpose drugs via a subpathway crosstalk network. The operation modes include 1) calculating centrality scores of SPs in the context of gene expression data to reflect the influence of SP crosstalk, 2) evaluating drug-disease reverse association based on disease- and drug-induced SPs weighted by the SP crosstalk, 3) identifying cancer candidate drugs through perturbation analysis. There are also several functions used to visualize the results.
How to cite:
Junwei Han (2021). DRviaSPCN: Drug Repurposing in Cancer via a Subpathway Crosstalk Network. R package version 0.1.5, https://cran.r-project.org/web/packages/DRviaSPCN. Accessed 14 Mar. 2026.
Previous versions and publish date:
0.1.0 (2021-12-09 10:00), 0.1.1 (2022-02-28 10:40), 0.1.2 (2022-03-03 17:00), 0.1.3 (2023-09-25 07:40), 0.1.4 (2024-01-13 06:00)
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Complete documentation for DRviaSPCN
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