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AllelicSeries  

Allelic Series Test
View on CRAN: Click here


Download and install AllelicSeries package within the R console
Install from CRAN:
install.packages("AllelicSeries")

Install from Github:
library("remotes")
install_github("cran/AllelicSeries")

Install by package version:
library("remotes")
install_version("AllelicSeries", "0.1.1.5")



Attach the package and use:
library("AllelicSeries")
Maintained by
Zachary McCaw
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2023-01-13
Latest Update: 2025-04-02
Description:
Implementation of gene-level rare variant association tests targeting allelic series: genes where increasingly deleterious mutations have increasingly large phenotypic effects. The COding-variant Allelic Series Test (COAST) operates on the benign missense variants (BMVs), deleterious missense variants (DMVs), and protein truncating variants (PTVs) within a gene. COAST uses a set of adjustable weights that tailor the test towards rejecting the null hypothesis for genes where the average magnitude of effect increases monotonically from BMVs to DMVs to PTVs. See McCaw ZR, O
How to cite:
Zachary McCaw (2023). AllelicSeries: Allelic Series Test. R package version 0.1.1.5, https://cran.r-project.org/web/packages/AllelicSeries. Accessed 16 Jul. 2026.
Previous versions and publish date:
0.0.2.2 (2023-01-13 20:00), 0.0.3.0 (2023-05-01 23:50), 0.0.4.1 (2023-10-06 08:40), 0.1.0.2 (2024-10-22 18:30), 0.1.1.1 (2024-11-22 04:20), 0.1.1.2 (2024-11-23 16:20), (2026-07-09 07:57)
Other packages that cited AllelicSeries R package
View AllelicSeries citation profile
Other R packages that AllelicSeries depends, imports, suggests or enhances
Complete documentation for AllelicSeries
Functions, R codes and Examples using the AllelicSeries R package
Some associated functions: ASBT . ASKAT . Aggregator . AllelicSeries-help . AllelicSeries-package . COAST . CalcRegParam . CheckInputs . Comparator . DGP . FilterGenos . GenAnno . GenCovar . GenGeno . GenGenoMat . GenPheno . OLS . ResidVar . Score . 
Some associated R codes: RcppExports.R . allelic_series_test.R . allelicseries-package.R . comparators.R . generate_data.R . input_checks.R . utilities.R .  Full AllelicSeries package functions and examples
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