Other packages > Find by keyword >

ActiveDriver  

Finding Cancer Driver Proteins with Enriched Mutations in Post-Translational Modification Sites
View on CRAN: Click here


Download and install ActiveDriver package within the R console
Install from CRAN:
install.packages("ActiveDriver")

Install from Github:
library("remotes")
install_github("cran/ActiveDriver")

Install by package version:
library("remotes")
install_version("ActiveDriver", "1.0.0")



Attach the package and use:
library("ActiveDriver")
Maintained by
Juri Reimand
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2017-08-23
Latest Update: 2017-08-23
Description:
A mutation analysis tool that discovers cancer driver genes with frequent mutations in protein signalling sites such as post-translational modifications (phosphorylation, ubiquitination, etc). The Poisson generalised linear regression model identifies genes where cancer mutations in signalling sites are more frequent than expected from the sequence of the entire gene. Integration of mutations with signalling information helps find new driver genes and propose candidate mechanisms to known drivers. Reference: Systematic analysis of somatic mutations in phosphorylation signaling predicts novel cancer drivers. Juri Reimand and Gary D Bader. Molecular Systems Biology (2013) 9:637 .
How to cite:
Juri Reimand (2017). ActiveDriver: Finding Cancer Driver Proteins with Enriched Mutations in Post-Translational Modification Sites. R package version 1.0.0, https://cran.r-project.org/web/packages/ActiveDriver. Accessed 15 Sep. 2026.
Previous versions and publish date:
No previous versions
Other packages that cited ActiveDriver R package
View ActiveDriver citation profile
Other R packages that ActiveDriver depends, imports, suggests or enhances
Complete documentation for ActiveDriver
Functions, R codes and Examples using the ActiveDriver R package
Some associated functions: ActiveDriver . kinase_domains . mutations . phosphosites . read_fasta . sequence_disorder . sequences . 
Some associated R codes: ActiveDriver.R .  Full ActiveDriver package functions and examples
Downloads during the last 30 days

Today's Hot Picks in Authors and Packages

RXshrink  
Maximum Likelihood Shrinkage using Generalized Ridge or Least Angle Regression
Functions are provided to calculate and display ridge TRACE Diagnostics for a variety of alternativ ...
Download / Learn more Package Citations See dependency  
quickcode  
Quick and Essential 'R' Tricks for Better Scripts
The NOT functions, 'R' tricks and a compilation of some simple quick plus often used 'R' codes to im ...
Download / Learn more Package Citations See dependency  
AFR  
Toolkit for Regression Analysis of Kazakhstan Banking Sector Data
Tool is created for regression, prediction and forecast analysis of macroeconomic and credit data. ...
Download / Learn more Package Citations See dependency  
objectSignals  
Observer Pattern for S4
A mutable Signal object can report changes to its state, clients could register functions so that t ...
Download / Learn more Package Citations See dependency  
SiER  
Signal Extraction Approach for Sparse Multivariate Response Regression
Methods for regression with high-dimensional predictors andunivariate or maltivariate response varia ...
Download / Learn more Package Citations See dependency  
functClust  
Functional Clustering of Redundant Components of a System
Cluster together the components that make up an interactivesystem on the basis of their functional r ...
Download / Learn more Package Citations See dependency  

28,565

R Packages

239,283

Dependencies

75,677

Author Associations

28,566

Publication Badges

© Copyright since 2022. All right reserved, rpkg.net.  Based in Cambridge, Massachusetts, USA